CAS nommer: 139755-83-2
Chemiese formule: C22H19N3O4
Molekulêre gewig: 389.4
Inhoud: 99.5% Sildenafil sitraat, Viagra
Oplosbaarheid: Bietjie oplosbaar in water, metanol; baie effens oplosbaar in etanol, chloroform
Voorkoms: Wit kristallyne poeier
Berging: skadu, beperkte bewaring.
Gebruik: Viagra (Sildenafil sitraat) is 'n middel wat gebruik word om erektiele disfunksie te behandel (impotensie) in males and pulmonary arterial
hipertensie (PAH).
Sildenafil sitraat, sold as Viagra, Sildenafil is an oral drug for the treatment of ED, used in the treatment of erectile dysfunction and premature ejaculation, erektiele funksie inkorting en premature ejakulasie het baie beduidende verbeterings. Daar is verby 1500 dokumente om die veroorsaak deur verskillende oorsake te bewys impotensie voortydige ejakulasie,geweet die suksessyfer is bo 80%, en toon die betroubare genesende effek daarvan, deur die gebruik van meer as 20 miljoen mense wêreldwyd, het sy langtermynstabiliteit bewys, die veiligheid van 25 aan 60 minute se werk funksie om saam te val met 'n tyd wat nodig is vir voorspel, het die tydaanpassing in die hoogste geneesmiddelkonsentrasietyd geken, help beide man en vrou 'n bevredigende sekslewe.
The primary indication of sildenafil is treatment of erectile dysfunction (inability to sustain a satisfactory erection to complete intercourse). Its use is now standard treatment for erectile dysfunction in all settings, including diabetes.It acts by inhibiting cGMP-specific phosphodiesterase type 5 (PDE5), an enzyme that promotes degradation of cGMP, which regulates blood flow in the penis.
As well as erectile dysfunction, sildenafil citrate is also effective in the rare disease pulmonary arterial hypertension. It relaxes the arterial wall, leading to decreased pulmonary arterial resistance and pressure. This, op sy beurt, reduces the workload of the right ventricle of the heart and improves symptoms of right-sided heart failure. Because PDE5 is primarily distributed within the arterial wall smooth muscle of the lungs and penis, sildenafil acts selectively in both these areas without inducing vasodilation in other areas of the body. Pfizer submitted an additional registration for sildenafil to the United States Food and Drug Administration (FDA), and sildenafil was approved for this indication in June 2005. The preparation is named Revatio, to avoid confusion with Viagra, and the 20-mg tablets are white and round. Sildenafil joins bosentan and prostacyclin-based therapies for this condition.
Sildenafil is used to treat high blood pressure in the lungs (pulmonary hypertension). It works by relaxing and widening the blood vessels in your lungs which allows the blood to flow more easily. Decreasing high blood pressure in the lungs allows your heart and lungs to work better and improves your ability to exercise.
