Številka CAS: 139755-83-2
Kemijska formula: C22H19N3O4
Molekulska teža: 389.4
Vsebina: 99.5% Sildenafil citrate, Viagra
Topnost: Slightly soluble in water, metanol; very slightly soluble in ethanol, chloroform
Videz: Bel kristalinični prah
Shranjevanje: senčenje, omejeno ohranjanje.
Uporaba: Viagra (Sildenafil citrate) is a drug used to treat erectile dysfunction (impotence) in males and pulmonary arterial
hypertension (PAH).
Sildenafil citrate, sold as Viagra, Sildenafil is an oral drug for the treatment of ED, used in the treatment of erectile dysfunction and premature ejaculation, poslabšanje erektilne funkcije in prezgodnja ejakulacija ima zelo pomembne izboljšave. Obstaja več 1500 dokumenti, ki dokazujejo impotenco zaradi različnih vzrokov prezgodnjo ejakulacijo,vedel, da je stopnja uspešnosti nad 80%, in pokažejo njegov zanesljiv zdravilni učinek, z uporabo več kot 20 milijonov ljudi po vsem svetu, dokazal svojo dolgoročno stabilnost, varnost 25 do 60 minute delovne funkcije sovpadajo s časom, potrebnim za predigro, poznal prilagoditev časa v času najvišje koncentracije zdravila, pomagati možu in ženi do zadovoljivega spolnega življenja.
The primary indication of sildenafil is treatment of erectile dysfunction (inability to sustain a satisfactory erection to complete intercourse). Its use is now standard treatment for erectile dysfunction in all settings, including diabetes.It acts by inhibiting cGMP-specific phosphodiesterase type 5 (PDE5), an enzyme that promotes degradation of cGMP, which regulates blood flow in the penis.
As well as erectile dysfunction, sildenafil citrate is also effective in the rare disease pulmonary arterial hypertension. It relaxes the arterial wall, leading to decreased pulmonary arterial resistance and pressure. This, in turn, reduces the workload of the right ventricle of the heart and improves symptoms of right-sided heart failure. Because PDE5 is primarily distributed within the arterial wall smooth muscle of the lungs and penis, sildenafil acts selectively in both these areas without inducing vasodilation in other areas of the body. Pfizer submitted an additional registration for sildenafil to the United States Food and Drug Administration (FDA), and sildenafil was approved for this indication in June 2005. The preparation is named Revatio, to avoid confusion with Viagra, and the 20-mg tablets are white and round. Sildenafil joins bosentan and prostacyclin-based therapies for this condition.
Sildenafil is used to treat high blood pressure in the lungs (pulmonary hypertension). It works by relaxing and widening the blood vessels in your lungs which allows the blood to flow more easily. Decreasing high blood pressure in the lungs allows your heart and lungs to work better and improves your ability to exercise.
