CAS Number: 139755-83-2
Formulae chemica: C22H19N3O4
M. Pondus: 389.4
Content: 99.5% Sildenafil citrate, Viagra
Solubilitas: Leviter solutum in aqua, methanolum; leviter solutum in ethanol, chloroform
Aspectus: Album pulveris crystallini
Repono: obumbrationis, inclusi conservationem.
Usage: Viagra (Sildenafil citrate) Est medicamento ad facies Praesent (impotentia) in males and pulmonary arterial
hypertension (PAH).
Sildenafil citrate, sold as Viagra, Sildenafil is an oral drug for the treatment of ED, used in the treatment of erectile dysfunction and premature ejaculation, munus erectile deminutum et immatura ejaculatio valde significant incrementa. Sunt super 1500 documenta ad probandum per diversas causas impotentiam immaturam ejaculationem,sciebant autem victoria rate est supra 80%, et effectus suos certa curativa ostende, per usum plus 20 decies populum terrarum, probatum diu terminus stabilitatis, salus 25 to 60 opus minuta munus congruere cum tempore opus foreplay, sciebant tempus temperatio in summa medicamento concentration tempore, adiuva tam vir et uxor satis sexus vitae.
The primary indication of sildenafil is treatment of erectile dysfunction (inability to sustain a satisfactory erection to complete intercourse). Its use is now standard treatment for erectile dysfunction in all settings, including diabetes.It acts by inhibiting cGMP-specific phosphodiesterase type 5 (PDE5), an enzyme that promotes degradation of cGMP, which regulates blood flow in the penis.
As well as erectile dysfunction, sildenafil citrate is also effective in the rare disease pulmonary arterial hypertension. It relaxes the arterial wall, leading to decreased pulmonary arterial resistance and pressure. This, in turn, reduces the workload of the right ventricle of the heart and improves symptoms of right-sided heart failure. Because PDE5 is primarily distributed within the arterial wall smooth muscle of the lungs and penis, sildenafil acts selectively in both these areas without inducing vasodilation in other areas of the body. Pfizer submitted an additional registration for sildenafil to the United States Food and Drug Administration (FDA), and sildenafil was approved for this indication in June 2005. The preparation is named Revatio, to avoid confusion with Viagra, and the 20-mg tablets are white and round. Sildenafil joins bosentan and prostacyclin-based therapies for this condition.
Sildenafil is used to treat high blood pressure in the lungs (pulmonary hypertension). It works by relaxing and widening the blood vessels in your lungs which allows the blood to flow more easily. Decreasing high blood pressure in the lungs allows your heart and lungs to work better and improves your ability to exercise.
