Testolactone Acetate blocks the production of the hormone estrogen. Certain types of breast cancer require estrogen to grow.Testolactone is used to treat some types of breast cancer.Testolactone may also be used for purposes other than those listed in this medication guide.
Testolactone Acetate is a synthetic anti-neoplastic agent that is structurally distinct from the androgen steroid nucleus in possessing a six-membered lactone ring in place of the usual five-membered carbocyclic D-ring. Ten spyte van 'n mate van ooreenkoms met testosteroon, Testolaktoon het geen in vivo androgene effek nie. Geen ander hormonale effekte is gerapporteer in kliniese studies by pasiënte wat Testolaktoon ontvang het nie.
Testolaktoonasetaat word as 'n antineoplastiese middel geklassifiseer, wat beteken dat dit die groei van kwaadaardige selle stop of vertraag. Een voordeel van testolaktoon is dit, alhoewel dit met testosteroon verband hou, dit veroorsaak nie dat vroue manlike eienskappe soos 'n diep stem of gesigshare ontwikkel nie.
Testolaktoonasetaat is verwant aan die manlike hormoon testosteroon. Die manier waarop dit die groei van borskankerselle inhibeer, is nie duidelik nie. Egter, dit is bekend dat die hormoon estrogeen die groei van sommige borskankerselle stimuleer, en testolaktoon blyk te meng met estrogeenproduksie. The resulting reduction in estrogen levels may slow the growth of breast cancers sensitive to this hormone.
In breast cancer, Testolactone Acetate is a palliative treatment. This means that it helps relieve symptoms, but does not cure the cancer. It is effective only in about 15% of the women who take it. In these women, egter, it helps reduce the size of half or more tumors. Normally testolactone is used along with other chemotherapy drugs for fighting advanced breast cancer.
Testolactone comes as a 50 mg tablet. The dose will depend on the patient's body weight and her general health, as well as other drugs she may be taking. Egter, a standard dose is 250 mg (5 tablets) four times a day for three months. It takes at least several weeks before the drug begins to be effective.
