Nesiritide Acetate (BNP-32)
Synonyma:Peptide natriuretica,cerebrum;Cerebrum peptide natriuretica, humano;Cerebrum peptide natriuretica (1-32), humano;Cerebrum peptide natriuretica-32;Cerebrum peptide natriuretica-32 (humano);Brain(b-genus) peptide natriuretica 32 (humano);B-type (cerebrum) peptide natriuretica 32 (humano);Bnp human
Cas No. 114471-18-0
Formulae hypotheticae C143H244N50O42 S4
M. Pondus 3464.04
Puritas (HPLC) 98.0%min.
Species White pulveris
una immunditia(HPLC) 1.0%max
Amino Acidum compositione ±10% theoreticae
Peptide Content(N%) ≥78.0%
Aqua Content(Carolus Fischer) ≤6.0%
Acetate Content(HPIC) ≤15.0%
MS(ESI) Congruunt
Missa Libra 95.0~ 105.0%
Usage: Hemostatic, Antimicrobial
Nesiritide (Natrecor) est recombinante forma 32 amino acid humano B-type peptide natriuretica, quae plerumque fit per myocardium ventriculi. Nesiritide laborat ut faciliorem reddat liquorem cardiovascularem homeostasim per counterregulation systematis renin-angiotensin-aldoesteronis, movens cyclica guanosine monophosphate, ducit ad lenis musculus cellam relaxationem.
Neseritide creditum initio utilem esse ad defectum cordis congestivi acuti decompensati. Adprobata a Civitatibus Foederatis Americae cibum et medicamentum ad hanc rem in 2001 Post initial non-probante. Mense Iulio 2011 eventus maximi studii usque ad nesiritide in The New England Journal of Medicine editus est; demonstravit nesiritide cum mutatione mortalitatis vel re-hospitalisationum non sociari.
Maxime fortis angiotensin II vasoconstriction et incremento sanguinis pressura. Mechanismus est: 1. Ut corpus arteriolum contractio musculus lenis, auctus resistentia periphericis; 2. Auge igitur emissionem aldosterone adrenalis, sodium retention causing, auctus sanguine volumine; 3. Directe conferunt ad sodium renum tubi et aquae reabsorptionis; 4. Itaque centrum cerebri nervosi vasoconstrictoris sympathetici activitatem, causando augeri periphericis vascularium resistentia; 5. Medulla adrenalis incitare ad emissionem epinephrinam et norepinephrinem.
| Product Name |
Nesiritide Acetate (BNP-32) |
| Cas No. |
114471-18-0 |
| Formulae hypotheticae |
C143H244N50O42 S4 |
| M. Pondus |
3464.04 |
| Puritas (HPLC) |
97.0%min. |
| Aspectus |
Pulvis albus |
| una immunditia(HPLC) |
1.0%max |
| Amino Acidum Compositio |
± X% speculationis |
| Peptide Content(N%) |
≥78.0% |
| Aqua Content(Carolus Fischer) |
≤6.0% |
| Acetate Content(HPIC) |
≤15.0% |
| MS(ESI) |
Congruunt |
| Massa Libra |
95.0~105.0% |
