Nomen: Plecanatids
CAS No. :467426-54-6
Sequentia: H-Asn-Asp-Glu-Cys(1)-Glu-Leu-Cys(2)-Val-Asn-Val-Ala-Cys(1)-Thr-Gly-Cys(2)-Leu-OH
Formulae hypotheticae: C65H104N18O26S4
M. pondus : 1681.88
Puritas: >98.0%
Source: synthetica
Plecanatida est fabrica analogon uroguanylini humani, et similiter uroguanylin, plecanatidis functiones guanylate-C (GC-C) agonist. Utraque plecanatida et eius metabolita activa ligant ad GC-C et localiter agunt in superficie luminari epithelii intestinalis.. Activatio GC-C consequitur in incremento concentrationis intracellulares et extracellulares monophosphae cyclici guanosini. (cGMP).
Plecanatidis in adultis adhibetur ad constipationem idiopathicam chronicam tractandam (CIC; difficilis aut rari transitus tempus advenerit, quae durat 3 menses vel longiores et non ex morbo vel medicamento) et irritabilis alvus syndrome cum constipatione (IBS-C; a conditione quod stomachum dolorem vel cramps, bloating, et constipatio.)
Plecanatidis est in genere medicamenti quod dicitur guanylata cyclasi-C agonistae. It works by increasing the movement of food and waste through the stomach and intestines.
