Tadalafil CAS:171596-29-5

tadalafil (Tadalifil citrate), a phosphodiesterase type 5 inhibitör, is used to treat erectile dysfunction (ED) and decreased libido in males. Tadalafil works by aiding relaxation of blood vessels and increasing blood flow in the penis during sexual arousal, resulting in improved erectile function. Tadalafil is much longer lasting.

Tadalafil is used for Erectile dysfunction and pulmonary hypertension, the rapid absorption after oral administration, 2 hours to reach maximum observed plasma concentrations of average time after administration of (Cmax). Influence of absorption rate and degree is not affected by food tadalafil, so it can be with or without with clothes and food.

Tadalafil is an oral drug for the treatment of ED, used in the treatment of erectile dysfunction and premature ejaculation, Erektil fonksiyon bozukluğu ve erken boşalmada çok önemli iyileşmeler var. bitti 1500 İktidarsızlık, erken boşalma, farklı nedenlerden kaynaklandığını kanıtlayan belgeler, başarı oranının yukarıda olduğunu biliyordum 80%, ve güvenilir iyileştirici etkisini gösterin, fazlası kullanılarak 20 dünya çapında milyon insan, uzun vadeli istikrarını kanıtladı, güvenliği 25 ile 60 ön sevişme için gereken süreye denk gelecek şekilde çalışma dakikası işlevi, En yüksek ilaç konsantrasyonu zamanında zaman ayarlamasını biliyordu, hem karı hem de kocanın tatmin edici bir cinsel yaşam kurmasına yardımcı olun.

Since people who have taken tadalafil within the past 48 hours cannot take organic nitrates to relieve angina (such as glyceryl trinitrate spray), these patients should seek immediate medical attention if they experience anginal chest pain.In the event of a medical emergency, paramedics and medical personnel should be notified of any recent doses of tadalafil.

Tadalafil is metabolized predominantly by the hepatic CYP3A4 enzyme system. The presence of other drugs which induce this system can shorten tadalafil half-life and reduce serum levels, and hence efficacy, of the drug.

Tadalafil has been used in approximately 15,000 men participating in clinical trials, and over eight million men worldwide(primarily in the post-approval/post-marketing setting). The most common side effects when using tadalafil are headache, stomach discomfort or pain, indigestion, burping, acid reflux, back pain, muscle aches, flushing, and stuffy or runny nose. These side effects reflect the ability of PDE5 inhibition to cause vasodilation (cause blood vessels to widen), and usually go away after a few hours. Back pain and muscle aches can occur 12 ile 24 hours after taking the drug, and the symptom usually disappears after 48 saat.