Xylazine is an analogue of clonidine and an agonist at the α2 class of adrenergic receptor. It is used for sedation, anestesia, rilassamento muscolare, e analgesia in animali come i cavalli, bovini e altri mammiferi non umani.
Xylazine is recognized as a short-acting tranquilizer or sedative that provides significant pain relief. Acting as a muscle relaxant through its effects on the central nervous system, it is commonly used for short-term sedation, and treatment and management of colic.
Xylazine can be administered intravenously, intramuscularly, subcutaneously or orally. The commercial product contains 23.32 mg/ml xylazine hydrochloride in water based injectable solution. Xylazine can be obtained also as pure crystalline powder. There is a significant species dependent response to xylazine administration. Intramuscular dose of up to 0.3 mg/kg for cattle has been suggested by the manufacturer. The recommended doses for horses were 0.6 mg/kg and for sheep 1.0 mg/kg. For dogs the dose was even higher.Xylazine is an analogue of clonidine and an agonist at the α2 class of adrenergic receptor. It is used for sedation, anestesia, rilassamento muscolare, e analgesia in animali come i cavalli, bovini e altri mammiferi non umani. Veterinarians also use xylazine as an emetic, especially in cats.