Carbetocin Acetate
Séquence: Butyryl-Tyr(Me)-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (Sulfide bond between Butyryl-4-yl and Cys)
CAS: 37025-55-1
Apparence: Poudre blanche
EINECS: 253-312-6
M.F.: C45H69N11O12S
M.W.: 988.17
Specific Optical Rotation D(c=1,1%HAc): -38.0~-42.0°
Water Content(Karl Fischer): ≤5,0%
Acetate Content(by HPLC): ≤12.0%
Amino Acid Composition: ±10% of theoretical
Pureté (by HPLC): ≥98.0%
Single Impurity(by HPLC): ≤1,0%
Peptide Content(by N%): ≥80%
Essai(By Anhydrous, Acetic Acid-free ): 97.0~103,0%
Bacterial Endotoxins: ≤5EU/mg
Usage:An obstetric drug used to control postpartum hemorrhaging.
Carbetocin (AUBERGE, INTERDIRE) (brand names Duratocin, Pabal, Lonactene, Depotocin, Comoton, Decomoton), or 1-butanoic acid-2-(O-methy-L-tyrosine)-1-carbaoxytocin, is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) et, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
Carbetocin is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) et, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
