Acétate de carbétocine
Séquence: Butyryl-Tyr(Me)-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (Sulfide bond between Butyryl-4-yl and Cys)
CAS: 37025-55-1
Apparence: Poudre blanche
EINECS: 253-312-6
M.F.: C45H69N11O12S
M.W.: 988.17
Specific Optical Rotation D(c=1,1%HAc): -38.0~-42.0°
Teneur en eau(Karl Fischer): ≤5,0%
Contenu en acétate(par HPLC): ≤12,0%
Composition en acides aminés: ±10% de la théorique
Pureté (par HPLC): ≥98,0 %
Impureté unique(par HPLC): ≤1,0%
Contenu peptidique(by N%): ≥80%
Essai(Par anhydre, Sans acide acétique ): 97.0~103,0%
Bacterial Endotoxins: ≤5EU/mg
Usage:An obstetric drug used to control postpartum hemorrhaging.
Carbetocin (AUBERGE, INTERDIRE) (brand names Duratocin, Pabal, Lonactene, Depotocin, Comoton, Decomoton), or 1-butanoic acid-2-(O-methy-L-tyrosine)-1-carbaoxytocin, is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) et, conformément, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
Carbetocin is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) et, conformément, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
