Carbetocin Acetate
Sequenza: Butyryl-Tyr(Me)-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (Sulfide bond between Butyryl-4-yl and Cys)
CAS: 37025-55-1
Aspetto: Polvere bianca
EINECS: 253-312-6
MF: C45H69N11O12S
M.W.: 988.17
Specific Optical Rotation D(c=1,1%HAc): -38.0~-42.0°
Contenuto d'acqua(Karl Fisher): ≤5,0%
Contenuto di acetato(mediante HPLC): ≤12.0%
Amino Acid Composition: ±10% of theoretical
Purezza (mediante HPLC): ≥98,0%
Singola impurità(mediante HPLC): ≤1,0%
Peptide Content(by N%): ≥80%
Analisi(By Anhydrous, Acetic Acid-free ): 97.0~103,0%
Bacterial Endotoxins: ≤5EU/mg
Utilizzo:An obstetric drug used to control postpartum hemorrhaging.
Carbetocin (LOCANDA, DIVIETO) (brand names Duratocin, Pabal, Lonactene, Depotocin, Comoton, Decomoton), or 1-butanoic acid-2-(O-methy-L-tyrosine)-1-carbaoxytocin, is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) E, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
Carbetocin is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) E, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
