Carbetocin Acetate
Reeks: Butyryl-Tyr(Me)-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (Sulfide bond between Butyryl-4-yl and Cys)
CAS: 37025-55-1
Verschijning: Wit poeder
EINECS: 253-312-6
M.F.: C45H69N11O12S
M.W.: 988.17
Specific Optical Rotation D(c=1,1%HAc): -38.0~-42.0°
Waterinhoud(Karel Fischer): ≤5,0%
Acetaat inhoud(door HPLC): ≤12.0%
Aminozuursamenstelling: ±10% van theoretisch
Zuiverheid (door HPLC): ≥98,0%
Enkele onzuiverheid(door HPLC): ≤1,0%
Peptide-inhoud(by N%): ≥80%
Analyse(Door watervrij, Azijnzuurvrij ): 97.0~103,0%
Bacterial Endotoxins: ≤5EU/mg
Gebruik:An obstetric drug used to control postpartum hemorrhaging.
Carbetocin (HERBERG, VERBODEN) (brand names Duratocin, Pabal, Lonactene, Depotocin, Comoton, Decomoton), or 1-butanoic acid-2-(O-methy-L-tyrosine)-1-carbaoxytocin, is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) En, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
Carbetocin is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) En, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
