Carbetocin Acetate
Последователност: Butyryl-Tyr(аз)-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (Sulfide bond between Butyryl-4-yl and Cys)
CAS: 37025-55-1
Външен вид: Бял прах
EINECS: 253-312-6
М.Ф.: C45H69N11O12S
M.W.: 988.17
Specific Optical Rotation D(c=1,1%HAc): -38.0~-42.0°
Водно съдържание(Карл Фишер): ≤5,0%
Съдържание на ацетат(чрез HPLC): ≤12,0%
Аминокиселинен състав: ±10% от теоретичната
Чистота (чрез HPLC): ≥98,0%
Единична примес(чрез HPLC): ≤1,0%
Съдържание на пептиди(by N%): ≥80%
Анализ(By Anhydrous, Acetic Acid-free ): 97.0~103,0%
Bacterial Endotoxins: ≤5EU/mg
Използване:An obstetric drug used to control postpartum hemorrhaging.
Carbetocin (ИНН, БАН) (brand names Duratocin, Pabal, Lonactene, Depotocin, Comoton, Decomoton), or 1-butanoic acid-2-(O-methy-L-tyrosine)-1-carbaoxytocin, is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) и, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
Carbetocin is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) и, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
