Carbetocin Acetate
دنباله: بوتیریل-تیر(من)-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (پیوند سولفیدی بین Butyryl-4-yl و Cys)
CAS: 37025-55-1
ظاهر: پودر سفید
EINECS: 253-312-6
م.ف.: C45H69N11O12S
M.W.: 988.17
چرخش نوری خاص D(c=1.1% HAc): -38.0~-42.0°
محتوای آب(کارل فیشر): ≤5.0٪
محتوای استات(توسط HPLC): ≤12.0٪
ترکیب اسید آمینه: ± 10 درصد نظری
خلوص (توسط HPLC): ≥98.0٪
ناخالصی منفرد(توسط HPLC): ≤1.0٪
محتوای پپتید(توسط N%): ≥80%
سنجش(توسط Anhydrous, بدون اسید استیک ): 97.0~ 103.0٪
اندوتوکسین های باکتریایی: ≤5EU/mg
استفاده:An obstetric drug used to control postpartum hemorrhaging.
Carbetocin (INN, ممنوع کردن) (brand names Duratocin, Pabal, Lonactene, Depotocin, Comoton, Decomoton), or 1-butanoic acid-2-(O-methy-L-tyrosine)-1-carbaoxytocin, is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) و, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
Carbetocin is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) و, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
