Nomen: Dibucaine Hydrochloride
CAS Non.: 61-12-1
Formulae: C20H30ClN3O2
M. Pondus: 379.98
Synonyma: 4-Quinolinecarboxamide,2-butoxy-N-[2-(diethylamino)ethyl]-, monohydrochloride (9CI*);Cinchoninamide,2-butoxy-N-[2-(diethylamino)ethyl]-, monohydrochloride (8CI*);2-Butoxy-N-(2-diethylaminoethyl)cinchoninamide hydrochloride;2-Butoxy-N-(2-diethylaminoethyl)cinchoninicum acidum amidum hydrochloride;2-n-Butoxy-N-(2-diethylaminoethyl)cinchoninamide hydrochloride;Benzolin (loci Papaver);Cincaine;Cincainus chloride;Cinchocainehydrochloride;Cinchocainium chloridum;Nupercainehydrochloride;Patchwork;Percaine;Percamin S;Sovcain;Sovacaine;
EINECS: 200-498-1
Density: 1.071g/cm3
Liquefactio Point: 99-101 °C(lit.)
Dibucaine hydrochloride is a local anesthetic of the amide type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted. The drug blocks both the initiation and conduction of nerve impulses by decreasing the neuronal membrane's permeability to sodium ions. This reversibly stabilizes the membrane and inhibits depolarization, resulting in the failure of a propagated action potential and subsequent conduction blockade.
In combination sodium dibucaine hydrochloride is administered to dogs to induce rapid, humane, painless euthanasia. The euthanasia solution is toxic to wildlife. Euthanized animals must be properly disposed of by deep burial, incineration or other method in compliance with state and local laws.
1. Dibucaine hydrochloride is a local anesthetic of the amide-type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted.
2. The drug blocks both the initiation and conduction of nerve impulses by decreasing the neuronal membrane's permeability to sodium ions. This reversibly stabilizes the membrane and inhibits depolarization, resulting in the failure of a propagated action potential and subsequent conduction blockade. In combination sodium, dibucaine hydrochloride is administered to dogs to induce rapid, humane, painless euthanasia. The euthanasia solution is toxic to wildlife. Euthanized animals must be properly disposed of by deep burial, incineration, or other methods in compliance with state and local laws.
| Item |
Standard |
Test Proventus |
| Damnum in siccitate |
≤2.0% |
0.19% |
| Metalla gravis |
≤10 ppm |
<10ppm |
| Aquae |
≤1.0% |
0.10% |
| Cinis sulphated |
≤0.5%, determinari 1.0 g*. |
0.01% |
| Substantiae cognatae |
immunditiae non specificatae: ad invicem immunditiam |
≤0.10% |
<0.10% |
| Summa immunditia |
≤0.5% |
0.18% |
| Puritas |
≥99.0% |
99.70% |
| Assay |
99.0%~101.0% (anhydrous substantia). |
99.80% |
| Microbiologica Analysis |
| Totalis laminam comitem |
≤1000cfu/g* |
Obsequitur |
| Salmonella |
Absens |
Negative |
| Repono |
Serva in bene clausa, lux repugnans et airtight continentia. |
Obsequitur |
