Nome: Dibucaine Hydrochloride
Nº CAS: 61-12-1
Fórmula: C20H30ClN3O2
Peso molecular: 379.98
Sinônimos: 4-Quinolinacarboxamida,2-butoxi-N-[2-(dietilamino)etilo]-, monocloridrato (9IC);Cinchoninamida,2-butoxi-N-[2-(dietilamino)etilo]-, monocloridrato (8IC);2-Butoxi-N-(2-dietilaminoetil)cloridrato de cinchoninamida;2-Butoxi-N-(2-dietilaminoetil)cloridrato de amida de ácido cinconínico;2-n-Butoxi-N-(2-dietilaminoetil)cloridrato de cinchoninamida;Benzolim (anestésico local);Cincaína;Cloreto de cincaína;Cloridrato de cinchocaína;Cloreto de cinchocaínio;Cloridrato de nupercaína;Retalhos;Percaína;Percamina S;Sovcain;Sovacaína;
EINECS: 200-498-1
Densidade: 1.071g/cm3
Ponto de fusão: 99-101 °C(aceso.)
Dibucaine hydrochloride is a local anesthetic of the amide type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted. The drug blocks both the initiation and conduction of nerve impulses by decreasing the neuronal membrane's permeability to sodium ions. This reversibly stabilizes the membrane and inhibits depolarization, resulting in the failure of a propagated action potential and subsequent conduction blockade.
In combination sodium dibucaine hydrochloride is administered to dogs to induce rapid, humane, painless euthanasia. The euthanasia solution is toxic to wildlife. Euthanized animals must be properly disposed of by deep burial, incineration or other method in compliance with state and local laws.
1. Dibucaine hydrochloride is a local anesthetic of the amide-type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted.
2. The drug blocks both the initiation and conduction of nerve impulses by decreasing the neuronal membrane's permeability to sodium ions. This reversibly stabilizes the membrane and inhibits depolarization, resulting in the failure of a propagated action potential and subsequent conduction blockade. In combination sodium, dibucaine hydrochloride is administered to dogs to induce rapid, humane, painless euthanasia. The euthanasia solution is toxic to wildlife. Euthanized animals must be properly disposed of by deep burial, incineration, or other methods in compliance with state and local laws.
| Item |
Padrão |
Resultados do teste |
| Perda na secagem |
≤2,0% |
0.19% |
| Metais pesados |
≤10 ppm |
<10ppm |
| Água |
≤1,0% |
0.10% |
| Cinza sulfatada |
≤0,5%, determinado em 1.0 g. |
0.01% |
| Substâncias relacionadas |
Impurezas não especificadas: para cada impureza |
≤0,10% |
<0.10% |
| Impureza Total |
≤0,5% |
0.18% |
| Pureza |
≥99,0% |
99.70% |
| Ensaio |
99.0%~101,0% (substância anidra). |
99.80% |
| Análise Microbiológica |
| Contagem total de placas |
≤1000ufc/g |
Cumpre |
| Salmonela |
Ausente |
Negativo |
| Armazenar |
Conservar em local bem fechado, recipientes resistentes à luz e herméticos. |
Cumpre |
