نام: Dibucaine Hydrochloride
شماره CAS: 61-12-1
فرمول: C20H30ClN3O2
وزن مولکولی: 379.98
مترادف ها: 4-Quinolinecarboxamide,2-butoxy-N-[2-(دی اتیل آمینو)اتیل]-, monohydrochloride (9CI);Cinchoninamide,2-butoxy-N-[2-(دی اتیل آمینو)اتیل]-, monohydrochloride (8CI);2-Butoxy-N-(2-diethylaminoethyl)cinchoninamide hydrochloride;2-Butoxy-N-(2-diethylaminoethyl)cinchoninic acid amide hydrochloride;2-n-Butoxy-N-(2-diethylaminoethyl)cinchoninamide hydrochloride;Benzolin (local anesthetic);Cincaine;Cincaine chloride;Cinchocainehydrochloride;Cinchocainium chloride;Nupercainehydrochloride;Percain;Percaine;Percamin S;Sovcain;Sovcaine;
EINECS: 200-498-1
تراکم: 1.071g/cm3
نقطه ذوب: 99-101 درجه سانتی گراد(روشن شد)
Dibucaine hydrochloride is a local anesthetic of the amide type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted. The drug blocks both the initiation and conduction of nerve impulses by decreasing the neuronal membrane's permeability to sodium ions. This reversibly stabilizes the membrane and inhibits depolarization, resulting in the failure of a propagated action potential and subsequent conduction blockade.
In combination sodium dibucaine hydrochloride is administered to dogs to induce rapid, humane, painless euthanasia. The euthanasia solution is toxic to wildlife. Euthanized animals must be properly disposed of by deep burial, incineration or other method in compliance with state and local laws.
1. Dibucaine hydrochloride is a local anesthetic of the amide-type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted.
2. The drug blocks both the initiation and conduction of nerve impulses by decreasing the neuronal membrane's permeability to sodium ions. This reversibly stabilizes the membrane and inhibits depolarization, resulting in the failure of a propagated action potential and subsequent conduction blockade. In combination sodium, dibucaine hydrochloride is administered to dogs to induce rapid, humane, painless euthanasia. The euthanasia solution is toxic to wildlife. Euthanized animals must be properly disposed of by deep burial, incineration, or other methods in compliance with state and local laws.
| مورد |
استاندارد |
نتایج آزمون |
| ضرر در خشک شدن |
≤2.0٪ |
0.19% |
| فلزات سنگین |
≤10 ppm |
<10ppm |
| آب |
≤1.0٪ |
0.10% |
| خاکستر سولفاته |
≤0.5٪, determined on 1.0 g. |
0.01% |
| مواد مرتبط |
ناخالصی های نامشخص: for each impurity |
≤0.10٪ |
<0.10% |
| Total Impurity |
≤0.5٪ |
0.18% |
| خلوص |
≥99.0٪ |
99.70% |
| سنجش |
99.0%~ 101.0٪ (anhydrous substance). |
99.80% |
| Microbiological Analysis |
| تعداد کل بشقاب |
≤1000cfu/g |
مطابقت دارد |
| سالمونلا |
Absent |
منفی |
| ذخیره سازی |
Preserve in well-closed, light-resistant and airtight containers. |
مطابقت دارد |
