L-Trijodotironien(T3)
CAS NO:6893-02-3
Chemiese naam:3,3′,5-Triiodo-L-tironien, sodium salt
Molekulêre formule:C15H12I3NO4
Molekulêre gewig:650.97
Inhoud:(%):99
Kookpunt:205°C
Liothyronine is die kragtigste vorm van tiroïedhormoon. Chemies, dit is byna identies aan trijodotironien (T3). As sodanig, dit werk op die liggaam in om die basale metaboliese tempo te verhoog, beïnvloed proteïensintese en verhoog die liggaam se sensitiwiteit vir katekolamiene (soos adrenalien) deur toelatendheid. Die tiroïedhormone is noodsaaklik vir die behoorlike ontwikkeling en differensiasie van alle selle van die menslike liggaam. Hierdie hormone reguleer ook proteïen, vet, en koolhidraatmetabolisme, beïnvloed hoe menslike selle energieke verbindings gebruik.
T3 is a regulator of the oxidative metabolism of energy. When you take liothyronine sodium it will increase the uptake of nutrients into the mitochondria, which raises activity in the oxidative metabolic pathway. This causes everything to work harder within the organism and makes the body demand more fuel.
Liothyronine is used to treat an underactive thyroid (hipotireose). Dit vervang of verskaf meer tiroïedhormoon, which is normally made by the thyroid gland. Liothyronine is a man-made form of thyroid hormone.
Low thyroid hormone levels can occur naturally or when the thyroid gland is injured by radiation/medications or removed by surgery. Having enough thyroid hormone helps you stay healthy. For children, having enough thyroid hormone helps them grow and learn normally.
This medication is also used to treat other types of thyroid problems (soos sekere soorte goiters, skildklierkanker).
It can also be used to test for certain types of thyroid disease.This medication should not be used to treat infertility unless it is caused by low thyroid hormone levels.
| Item |
Spesifikasie |
Resultaat |
| Voorkoms |
'n Reuklose, amper wit of dofgeelkleurige poeier |
slaag |
| Oplosbaarheid |
1,Baie effens oplosbaar in water |
slaag |
| 2,effens oplosbaar in alkohol |
slaag |
| 3,feitlik onoplosbaar in die meeste ander organiese oplosmiddels |
slaag |
| 4,oplos in verdunde waterige natriumhidroksiedoplossings |
Slaag |
| Identifikasie |
a) Verhit omtrent 50 mg with a few drops of sulfuric acid in a |
slaag |
| porcelain crucible: violet dampe van jodium word ontwikkel. |
| b)Die retensietyd van die groot piek word aan die RS bevestig |
slaag |
| Verlies op droog |
Nie meer as 4.0% |
0.46% |
| [a]20/D |
+18 ~ +22o |
＋20.9o |
| C=1 in 1M HCl/EtOH 1:4 |
| Assay(HPLC) |
Nie minder as 95.0% |
99.18% |
| Levotiroksiennatrium |
Nie meer as 5.0% |
0.68% |
| Gevolgtrekking: |
Tot by die Standaard vir Uitvoer |
