Product Name :Calcitonin salmon
Trade nomen:Saleatonin
CAS Non.:47931-85-1
Formulae hypotheticae: C145H240N44O48S2
M. Pondus:3431.85g / mol
Puritas : 98% HPLC
Aspectus: Lyophilized pulveris
Typical usus:Curatio Osteoporosis
Calcitonin (salmon) is an hypocalcemic hormone produced by the parafollicular C cells of the thyroid or by the ultimobranchial bodies of nonmammalian vertebrates. Calcitonin decreases blood calcium and phosphate due to inhibition of resorption by osteoblasts and osteocytes. Calcitonin contains a single disulfide bond, which causes the amino terminus to assume the shape of a ring. Alternative splicing of the calcitonin pre-mRNA can yield a mRNA encoding calcitonin gene-related peptide; that peptide appears to function in the nervous and vascular systems. The calcitonin receptor has been cloned and shown to be a member of the seven-transmembrane, G protein-coupled receptor family.
-Treatment of postmenopausal women with osteoporosis at high risk for fracture
-Increase of bone mass in men with primary or hypogonadal osteoporosis at high risk for fracture
-Treatment of men and women with osteoporosis associated with sustained systemic glucocorticoid therapy at high risk for fracture
| Item |
Standard |
Test Proventus |
| Lepidium sativum |
A.H-NMR:Ad propinquos meos structuram |
Obsequitur |
|
B.LC-MS:Ad propinquos meos structuram |
Obsequitur |
|
C.The IR spectrum specimen idem esse debet cum eo quod vexillum referat; |
Obsequitur |
|
D.HPLC-ESI-MS
The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay. |
Obsequitur |
| Crystallinity |
occurret opus. |
Obsequitur |
| Damnum in siccitate |
≤2.0% |
0.19% |
| Metalla gravis |
≤10 ppm |
<10ppm |
| Aquae |
≤1.0% |
0.1% |
| Cinis sulphated |
≤0.5%, determinari 1.0 g*. |
0.009% |
| Substantiae cognatae |
immunditiae non specificatae: ad invicem immunditiam |
<0.10% |
|
Summa immunditia |
0.18% |
| Puritas |
≥99.0% |
99.7% |
| Assay |
99.0%~101.0% (anhydrous substantia). |
99.8% |
| Microbiologica Analysis |
|
|
| Totalis laminam comitem |
≤1000cfu/g* |
Obsequitur |
| Yeast and Moulds |
≤100cfu/g* |
Obsequitur |
| E. Coli. |
Absens |
Negative |
| Salmonella |
Absens |
Negative |
| S.aureus |
Absens |
Negative |
| Repono |
Serva in bene clausa, lux repugnans et airtight continentia. |
Obsequitur |
