Ürün Adı :Kalsitonin somonu
Trade Name:Saleatonin
CAS No.:47931-85-1
Moleküler Formül: C145H240N44O48S2
Molekül Ağırlığı:3431.85g/mol
Saflık : 98% HPLC
Dış görünüş: Lyophilized Powder
Tipik kullanım:Treatment of Osteoporosis
Calcitonin (salmon) is an hypocalcemic hormone produced by the parafollicular C cells of the thyroid or by the ultimobranchial bodies of nonmammalian vertebrates. Calcitonin decreases blood calcium and phosphate due to inhibition of resorption by osteoblasts and osteocytes. Calcitonin contains a single disulfide bond, which causes the amino terminus to assume the shape of a ring. Alternative splicing of the calcitonin pre-mRNA can yield a mRNA encoding calcitonin gene-related peptide; that peptide appears to function in the nervous and vascular systems. The calcitonin receptor has been cloned and shown to be a member of the seven-transmembrane, G protein-coupled receptor family.
-Treatment of postmenopausal women with osteoporosis at high risk for fracture
-Increase of bone mass in men with primary or hypogonadal osteoporosis at high risk for fracture
-Treatment of men and women with osteoporosis associated with sustained systemic glucocorticoid therapy at high risk for fracture
| Öğe |
Standart |
Test Sonuçları |
| Tanılama |
A.H-NMR:Comply with the structure |
Uyumludur |
|
B.LC-MS:Comply with the structure |
Uyumludur |
|
C. Numunenin IR spektrumu referans standardınınkiyle aynı olmalıdır.; |
Uyumludur |
|
D.HPLC-ESI-MS
The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay. |
Uyumludur |
| Crystallinity |
meets the requirements. |
Uyumludur |
| Kurutma kaybı |
≤%2,0 |
0.19% |
| Ağır metaller |
≤10 ppm |
<10ppm |
| su |
≤%1,0 |
0.1% |
| Sülfatlanmış kül |
≤%0,5, üzerinde belirlendi 1.0 G. |
0.009% |
| İlgili maddeler |
Belirtilmemiş safsızlıklar: her kirlilik için |
<0.10% |
|
Toplam Safsızlık |
0.18% |
| Saflık |
≥99.0% |
99.7% |
| tahlil |
99.0%~1,0 (susuz madde). |
99.8% |
| Microbiological Analysis |
|
|
| Toplam plaka sayısı |
≤1000cfu/g |
Uyumludur |
| Yeast and Moulds |
≤100cfu/g |
Uyumludur |
| e. Coli. |
Absent |
Negatif |
| Salmonella |
Absent |
Negatif |
| S.aureus |
Absent |
Negatif |
| Depolamak |
İyi kapalı olarak saklayın, ışığa dayanıklı ve hava geçirmez kaplar. |
Uyumludur |
