Cetrorelix acetate
英語の同義語: N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-ピリジニル)-D-alanyl-L-seryl-L-tyrosyl-N5-(アミノカルボニル)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide diacetate;Cetrorelix acetate;Cetrorenlin Acetate
CAS: 130143-01-0
アッセイ: 98%
分子式: C70H92N17O14
分子量:1551.16
使用法: Is to promote the GnRH receptor antagonist
Cetrorelix acetate is the acetic acid salt of cetrorelix. A gonadotrophin-releasing hormone (GnRH) antagonist, it is used for treatment of infertility and of hormone-sensitive cancers of the prostate and breast. It has a role as a GnRH antagonist and an antineoplastic agent. It is an oligopeptide and an acetate salt. It contains a cetrorelix.
The use of cetrorelix is contraindicated in severe renal impairment. It is not intended for women aged 65 years or older. Use in women with severe allergic conditions is not recommended. Use with caution in women with active allergies or history of allergies.
| アイテム |
仕様 |
結果 |
| 外観 |
白い粉 |
白い粉 |
| Identity by HPLC |
The retention is same with the reference substance |
適合 |
| Specific Optical Rotation |
-20 to -30°(c=1,50%HAc) |
-26.5° |
| アミノ酸組成 |
±20% of theoretical |
適合 |
| 純度 (HPLCによる) |
≧98.0% |
99.11% |
| Related Substance(By HPLC) |
総不純物(%)≤2.0%
Largest Single Impurity(%)≤1.0% |
0.89%
0.25% |
| アセテート含有量 (HPLCによる) |
≤15.0% |
9.7% |
| 水分含有量 (by Karl Fischer) |
≤10.0% |
2.2% |
| Bacterial Endotoxins |
≤5EU/mg |
適合 |
| ペプチド含有量(N%) |
≥85.0% |
86.5% |
