Cetroreliks acetat
angleški sinonimi: N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-piridinil)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide diacetate;Cetroreliks acetat;Cetrorenlin Acetate
CAS: 130143-01-0
Test: 98%
Molekularna formula: C70H92N17O14
Molekulska teža:1551.16
Uporaba: Is to promote the GnRH receptor antagonist
Cetrorelix acetate is the acetic acid salt of cetrorelix. A gonadotrophin-releasing hormone (GnRH) antagonist, it is used for treatment of infertility and of hormone-sensitive cancers of the prostate and breast. It has a role as a GnRH antagonist and an antineoplastic agent. It is an oligopeptide and an acetate salt. It contains a cetrorelix.
The use of cetrorelix is contraindicated in severe renal impairment. It is not intended for women aged 65 years or older. Use in women with severe allergic conditions is not recommended. Use with caution in women with active allergies or history of allergies.
| Predmeti |
Specifikacije |
Rezultati |
| Videz |
Bel prah |
Bel prah |
| Identity by HPLC |
The retention is same with the reference substance |
Ustreza |
| Specific Optical Rotation |
-20 to -30°(c=1,50%HAc) |
-26.5° |
| Aminokislinska sestava |
±20% of theoretical |
Ustreza |
| Čistost (s HPLC) |
≥98,0 % |
99.11% |
| Sorodna snov(S HPLC) |
Skupne nečistoče(%)≤2,0 %
Largest Single Impurity(%)≤1,0 % |
0.89%
0.25% |
| Vsebnost acetata (s HPLC) |
≤15,0 % |
9.7% |
| Vsebnost vode (by Karl Fischer) |
≤10,0 % |
2.2% |
| Bacterial Endotoxins |
≤5EU/mg |
Ustreza |
| Vsebnost peptidov(N %) |
≥85.0% |
86.5% |
