Cetrorelix acetate
Sinônimos em inglês: N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide diacetate;Cetrorelix acetate;Cetrorenlin Acetate
CAS: 130143-01-0
Ensaio: 98%
Fórmula Molecular: C70H92N17O14
Peso molecular:1551.16
Uso: Is to promote the GnRH receptor antagonist
Cetrorelix acetate is the acetic acid salt of cetrorelix. A gonadotrophin-releasing hormone (GnRH) antagonist, it is used for treatment of infertility and of hormone-sensitive cancers of the prostate and breast. It has a role as a GnRH antagonist and an antineoplastic agent. It is an oligopeptide and an acetate salt. It contains a cetrorelix.
The use of cetrorelix is contraindicated in severe renal impairment. It is not intended for women aged 65 years or older. Use in women with severe allergic conditions is not recommended. Use with caution in women with active allergies or history of allergies.
| Unid |
Especificações |
Resultados |
| Aparência |
Pó branco |
Pó branco |
| Identity by HPLC |
The retention is same with the reference substance |
Em conformidade |
| Specific Optical Rotation |
-20 to -30°(c=1,50%HAc) |
-26.5° |
| Composição de aminoácidos |
±20% of theoretical |
Em conformidade |
| Pureza (por HPLC) |
≥98,0% |
99.11% |
| Substância Relacionada(Por HPLC) |
Impurezas Totais(%)≤2,0%
Largest Single Impurity(%)≤1,0% |
0.89%
0.25% |
| Conteúdo de acetato (por HPLC) |
≤15,0% |
9.7% |
| Conteúdo de água (by Karl Fischer) |
≤10,0% |
2.2% |
| Endotoxinas Bacterianas |
≤5EU/mg |
Em conformidade |
| Conteúdo Peptídico(N%) |
≥85.0% |
86.5% |
