ستررولیکس استات
مترادف های انگلیسی: N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide diacetate;ستررولیکس استات;Cetrorenlin Acetate
CAS: 130143-01-0
سنجش: 98%
فرمول مولکولی: C70H92N17O14
وزن مولکولی:1551.16
استفاده: Is to promote the GnRH receptor antagonist
Cetrorelix acetate is the acetic acid salt of cetrorelix. A gonadotrophin-releasing hormone (GnRH) antagonist, it is used for treatment of infertility and of hormone-sensitive cancers of the prostate and breast. It has a role as a GnRH antagonist and an antineoplastic agent. It is an oligopeptide and an acetate salt. It contains a cetrorelix.
The use of cetrorelix is contraindicated in severe renal impairment. It is not intended for women aged 65 years or older. Use in women with severe allergic conditions is not recommended. Use with caution in women with active allergies or history of allergies.
| موارد |
مشخصات |
نتایج |
| ظاهر |
پودر سفید |
پودر سفید |
| Identity by HPLC |
The retention is same with the reference substance |
مطابقت دارد |
| Specific Optical Rotation |
-20 to -30°(c=1,50%HAc) |
-26.5درجه |
| ترکیب اسید آمینه |
±20% of theoretical |
مطابقت دارد |
| خلوص (توسط HPLC) |
≥98.0٪ |
99.11% |
| ماده مرتبط(توسط HPLC) |
کل ناخالصی ها(%)≤2.0٪
Largest Single Impurity(%)≤1.0٪ |
0.89%
0.25% |
| محتوای استات (توسط HPLC) |
≤15.0٪ |
9.7% |
| محتوای آب (by Karl Fischer) |
≤10.0٪ |
2.2% |
| اندوتوکسین های باکتریایی |
≤5EU/mg |
مطابقت دارد |
| محتوای پپتید(N%) |
≥85.0% |
86.5% |
