Cetrorelix acetate
Englische Synonyme: N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-Pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide diacetate;Cetrorelix acetate;Cetrorenlin Acetate
CAS: 130143-01-0
Test: 98%
Molekulare Formel: C70H92N17O14
Molekulargewicht:1551.16
Verwendung: Is to promote the GnRH receptor antagonist
Cetrorelix acetate is the acetic acid salt of cetrorelix. A gonadotrophin-releasing hormone (GnRH) antagonist, it is used for treatment of infertility and of hormone-sensitive cancers of the prostate and breast. It has a role as a GnRH antagonist and an antineoplastic agent. It is an oligopeptide and an acetate salt. It contains a cetrorelix.
The use of cetrorelix is contraindicated in severe renal impairment. It is not intended for women aged 65 years or older. Use in women with severe allergic conditions is not recommended. Use with caution in women with active allergies or history of allergies.
| Artikel |
Spezifikationen |
Ergebnisse |
| Aussehen |
Weißes Pulver |
Weißes Pulver |
| Identity by HPLC |
The retention is same with the reference substance |
Konform |
| Spezifische optische Drehung |
-20 to -30°(c=1,50%HAc) |
-26.5° |
| Aminosäurezusammensetzung |
±20% of theoretical |
Konform |
| Reinheit (durch HPLC) |
≥98,0 % |
99.11% |
| Verwandte Substanz(Durch HPLC) |
Gesamtverunreinigungen(%)≤2,0 %
Largest Single Impurity(%)≤1,0 % |
0.89%
0.25% |
| Acetatgehalt (durch HPLC) |
≤15,0 % |
9.7% |
| Wassergehalt (by Karl Fischer) |
≤10,0 % |
2.2% |
| Bakterielle Endotoxine |
≤5EU/mg |
Konform |
| Peptidgehalt(N%) |
≥85.0% |
86.5% |
