Setrorelix asetat
İngilizce Eşanlamlılar: N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide diacetate;Setrorelix asetat;Cetrorenlin Acetate
CAS: 130143-01-0
tahlil: 98%
Moleküler Formül: C70H92N17O14
Molekül Ağırlığı:1551.16
Kullanım: Is to promote the GnRH receptor antagonist
Cetrorelix acetate is the acetic acid salt of cetrorelix. A gonadotrophin-releasing hormone (GnRH) antagonist, it is used for treatment of infertility and of hormone-sensitive cancers of the prostate and breast. It has a role as a GnRH antagonist and an antineoplastic agent. It is an oligopeptide and an acetate salt. It contains a cetrorelix.
The use of cetrorelix is contraindicated in severe renal impairment. It is not intended for women aged 65 years or older. Use in women with severe allergic conditions is not recommended. Use with caution in women with active allergies or history of allergies.
| Öğeler |
Özellikler |
Sonuçlar |
| Dış görünüş |
Beyaz toz |
Beyaz toz |
| Identity by HPLC |
The retention is same with the reference substance |
Uygun |
| Specific Optical Rotation |
-20 to -30°(c=1,50%HAc) |
-26.5° |
| Amino Asit Bileşimi |
±20% of theoretical |
Uygun |
| Saflık (by HPLC) |
≥�,0 |
99.11% |
| İlgili Madde(HPLC'ye göre) |
Toplam Safsızlıklar(%)≤%2,0
Largest Single Impurity(%)≤%1,0 |
0.89%
0.25% |
| Asetat İçeriği (by HPLC) |
≤,0 |
9.7% |
| Su İçeriği (by Karl Fischer) |
≤,0 |
2.2% |
| Bacterial Endotoxins |
≤5EU/mg |
Uygun |
| Peptide Content(N%) |
≥85.0% |
86.5% |
