Cetrorelix acetate
Angielskie synonimy: N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide diacetate;Cetrorelix acetate;Cetrorenlin Acetate
CAS: 130143-01-0
Analiza: 98%
Formuła molekularna: C70H92N17O14
Masa cząsteczkowa:1551.16
Stosowanie: Is to promote the GnRH receptor antagonist
Cetrorelix acetate is the acetic acid salt of cetrorelix. A gonadotrophin-releasing hormone (GnRH) antagonist, it is used for treatment of infertility and of hormone-sensitive cancers of the prostate and breast. It has a role as a GnRH antagonist and an antineoplastic agent. It is an oligopeptide and an acetate salt. It contains a cetrorelix.
The use of cetrorelix is contraindicated in severe renal impairment. It is not intended for women aged 65 years or older. Use in women with severe allergic conditions is not recommended. Use with caution in women with active allergies or history of allergies.
| Rzeczy |
Dane techniczne |
Wyniki |
| Wygląd |
Biały proszek |
Biały proszek |
| Identity by HPLC |
The retention is same with the reference substance |
Zgodny |
| Specyficzna rotacja optyczna |
-20 to -30°(c=1,50%HAc) |
-26.5° |
| Skład aminokwasów |
±20% of theoretical |
Zgodny |
| Czystość (metodą HPLC) |
≥98,0% |
99.11% |
| Powiązana substancja(Za pomocą HPLC) |
Całkowite zanieczyszczenia(%)≤2,0%
Largest Single Impurity(%)≤1,0% |
0.89%
0.25% |
| Zawartość octanu (metodą HPLC) |
≤15,0% |
9.7% |
| Zawartość wody (by Karl Fischer) |
≤10,0% |
2.2% |
| Endotoksyny bakteryjne |
≤5EU/mg |
Zgodny |
| Zawartość peptydów(N%) |
≥85.0% |
86.5% |
