Cetrorelix acetat
Sinonime în engleză: N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-piridinil)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonil)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide diacetate;Cetrorelix acetat;Cetrorenlin Acetate
CAS: 130143-01-0
Test: 98%
Formula moleculară: C70H92N17O14
Greutate moleculară:1551.16
Utilizare: Is to promote the GnRH receptor antagonist
Cetrorelix acetate is the acetic acid salt of cetrorelix. A gonadotrophin-releasing hormone (GnRH) antagonist, it is used for treatment of infertility and of hormone-sensitive cancers of the prostate and breast. It has a role as a GnRH antagonist and an antineoplastic agent. It is an oligopeptide and an acetate salt. It contains a cetrorelix.
The use of cetrorelix is contraindicated in severe renal impairment. It is not intended for women aged 65 years or older. Use in women with severe allergic conditions is not recommended. Use with caution in women with active allergies or history of allergies.
| Articole |
Specificații |
Rezultate |
| Aspect |
Pulbere albă |
Pulbere albă |
| Identity by HPLC |
The retention is same with the reference substance |
Se conformează |
| Rotatie optică specifică |
-20 to -30°(c=1,50%HAc) |
-26.5° |
| Compoziția aminoacizilor |
±20% of theoretical |
Se conformează |
| Puritate (prin HPLC) |
≥98,0% |
99.11% |
| Related Substance(Prin HPLC) |
Impurități totale(%)≤2,0%
Largest Single Impurity(%)≤1,0% |
0.89%
0.25% |
| Conținut de acetat (prin HPLC) |
≤15,0% |
9.7% |
| Conținut de apă (by Karl Fischer) |
≤10,0% |
2.2% |
| Endotoxine bacteriene |
≤5EU/mg |
Se conformează |
| Conținutul de peptide(N%) |
≥85.0% |
86.5% |
