Cetrorelix acetate
Английские синонимы: N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-пиридинил)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide diacetate;Cetrorelix acetate;Cetrorenlin Acetate
КАС: 130143-01-0
Анализ: 98%
Молекулярная формула: C70H92N17O14
Молекулярный вес:1551.16
Использование: Is to promote the GnRH receptor antagonist
Cetrorelix acetate is the acetic acid salt of cetrorelix. A gonadotrophin-releasing hormone (ГнРГ) antagonist, it is used for treatment of infertility and of hormone-sensitive cancers of the prostate and breast. It has a role as a GnRH antagonist and an antineoplastic agent. It is an oligopeptide and an acetate salt. It contains a cetrorelix.
The use of cetrorelix is contraindicated in severe renal impairment. It is not intended for women aged 65 years or older. Use in women with severe allergic conditions is not recommended. Use with caution in women with active allergies or history of allergies.
| Предметы |
Технические характеристики |
Результаты |
| Появление |
Белый порошок |
Белый порошок |
| Identity by HPLC |
The retention is same with the reference substance |
Соответствует |
| Specific Optical Rotation |
-20 to -30°(c=1,50%HAc) |
-26.5° |
| Аминокислотный состав |
±20% of theoretical |
Соответствует |
| Чистота (методом ВЭЖХ) |
≥98,0% |
99.11% |
| Related Substance(By HPLC) |
Всего примесей(%)≤2,0%
Largest Single Impurity(%)≤1,0% |
0.89%
0.25% |
| Содержание ацетата (методом ВЭЖХ) |
≤15.0% |
9.7% |
| Содержание воды (by Karl Fischer) |
≤10,0% |
2.2% |
| Bacterial Endotoxins |
≤5EU/mg |
Соответствует |
| Содержание пептидов(Н%) |
≥85.0% |
86.5% |
