Cetrorelix acetate
Английски синоними: N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-пиридинил)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide diacetate;Cetrorelix acetate;Cetrorenlin Acetate
CAS: 130143-01-0
Анализ: 98%
Молекулярна формула: C70H92N17O14
Молекулно тегло:1551.16
Използване: Is to promote the GnRH receptor antagonist
Cetrorelix acetate is the acetic acid salt of cetrorelix. A gonadotrophin-releasing hormone (GnRH) antagonist, it is used for treatment of infertility and of hormone-sensitive cancers of the prostate and breast. It has a role as a GnRH antagonist and an antineoplastic agent. It is an oligopeptide and an acetate salt. It contains a cetrorelix.
The use of cetrorelix is contraindicated in severe renal impairment. It is not intended for women aged 65 years or older. Use in women with severe allergic conditions is not recommended. Use with caution in women with active allergies or history of allergies.
| Предмети |
Спецификации |
Резултати |
| Външен вид |
Бял прах |
Бял прах |
| Identity by HPLC |
The retention is same with the reference substance |
Съответства |
| Specific Optical Rotation |
-20 to -30°(c=1,50%HAc) |
-26.5° |
| Аминокиселинен състав |
±20% of theoretical |
Съответства |
| Чистота (чрез HPLC) |
≥98,0% |
99.11% |
| Свързано вещество(Чрез HPLC) |
Общо примеси(%)≤2,0%
Largest Single Impurity(%)≤1,0% |
0.89%
0.25% |
| Съдържание на ацетат (чрез HPLC) |
≤15,0% |
9.7% |
| Водно съдържание (by Karl Fischer) |
≤10,0% |
2.2% |
| Bacterial Endotoxins |
≤5EU/mg |
Съответства |
| Съдържание на пептиди(N%) |
≥85.0% |
86.5% |
