Cetrorelix acetate
Sinónimos en inglés: N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-piridinilo)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide diacetate;Cetrorelix acetate;Cetrorenlin Acetate
CAS: 130143-01-0
Ensayo: 98%
Fórmula molecular: C70H92N17O14
Peso molecular:1551.16
Uso: Is to promote the GnRH receptor antagonist
Cetrorelix acetate is the acetic acid salt of cetrorelix. A gonadotrophin-releasing hormone (GnRH) antagonist, it is used for treatment of infertility and of hormone-sensitive cancers of the prostate and breast. It has a role as a GnRH antagonist and an antineoplastic agent. It is an oligopeptide and an acetate salt. It contains a cetrorelix.
The use of cetrorelix is contraindicated in severe renal impairment. It is not intended for women aged 65 years or older. Use in women with severe allergic conditions is not recommended. Use with caution in women with active allergies or history of allergies.
| Elementos |
Presupuesto |
Resultados |
| Apariencia |
polvo blanco |
polvo blanco |
| Identity by HPLC |
The retention is same with the reference substance |
Cumple |
| Specific Optical Rotation |
-20 to -30°(c=1,50%HAc) |
-26.5° |
| Composición de aminoácidos |
±20% of theoretical |
Cumple |
| Pureza (por HPLC) |
≥98,0% |
99.11% |
| Sustancia relacionada(By HPLC) |
Impurezas totales(%)≤2,0%
Largest Single Impurity(%)≤1,0% |
0.89%
0.25% |
| Contenido de acetato (por HPLC) |
≤15,0% |
9.7% |
| Contenido de agua (by Karl Fischer) |
≤10,0% |
2.2% |
| Endotoxinas bacterianas |
≤5UE/mg |
Cumple |
| Contenido de péptidos(NORTE%) |
≥85.0% |
86.5% |
